Synergistic effect of carbon nanotubes, copper and silver nanoparticles as an efficient electrochemical sensor for the trace recognition of amlodipine besylate drug

Gowhar A. Naikoo; Umar J. Pandit; Mehraj U.D. Sheikh; Israr Ul Hassan; Gulzar A. Khan; Ajmal R. Bhat; Ratnesh Das; Ridha Horchani

doi:10.1007/s42452-020-2807-z

Synergistic effect of carbon nanotubes, copper and silver nanoparticles as an efficient electrochemical sensor for the trace recognition of amlodipine besylate drug

Gowhar A. Naikoo^*, Umar J. Pandit, Mehraj U.D. Sheikh, Israr Ul Hassan, Gulzar A. Khan, Ajmal R. Bhat, Ratnesh Das, Ridha Horchani

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

The electrochemically functionalized multiwalled carbon nanotubes/copper nanoparticles (fMWCNT/CuNPs) carbon paste electrode (fMWCNT/CuNPs-CPE) was successfully modified by silver nanoparticles (AgNPs) via electrocatalytic process. The formation of modified electrode (AgNPs/fMWCNT/Cu NP-CPE) was observed by Field Emission Scanning Electron Microscopy and X-ray diffraction techniques. The as-prepared electrodes were explored for the trace recognition of calcium channel blocker drug amlodipine besylate (ADB) using cyclic voltammetry and electrochemical impedance spectroscopy measurements. Kinetic parameters like electron transfer coefficient (α), charge due to adsorption (Q_ads), surface coverage (Γ), charge transfer coefficient (R_ct), and apparent electron-transfer rate constant (k_app) for the designed electrodes were evaluated. The nanoparticles based electrochemical sensor displayed high sensitivity, good selectivity and favorable catalytic ability for the oxidation of amlodipine besylate. The fabricated electrodes showed good reproducibility and stability towards the determination of anti-hypertensive drug ADB.

Original language	English
Article number	983
Journal	SN Applied Sciences
Volume	2
Issue number	5
DOIs	https://doi.org/10.1007/s42452-020-2807-z
Publication status	Published - May 2020
Externally published	Yes

Keywords

Amlodipine besylate
Electrochemical sensor
Functionalized carbon nanotubes

ASJC Scopus subject areas

Engineering(all)
Environmental Science(all)
Materials Science(all)
Physics and Astronomy(all)
Chemical Engineering(all)
Earth and Planetary Sciences(all)

Access to Document

10.1007/s42452-020-2807-z

Cite this

@article{9d2efffee7d040b1b578e949919ba1cf,

title = "Synergistic effect of carbon nanotubes, copper and silver nanoparticles as an efficient electrochemical sensor for the trace recognition of amlodipine besylate drug",

abstract = "The electrochemically functionalized multiwalled carbon nanotubes/copper nanoparticles (fMWCNT/CuNPs) carbon paste electrode (fMWCNT/CuNPs-CPE) was successfully modified by silver nanoparticles (AgNPs) via electrocatalytic process. The formation of modified electrode (AgNPs/fMWCNT/Cu NP-CPE) was observed by Field Emission Scanning Electron Microscopy and X-ray diffraction techniques. The as-prepared electrodes were explored for the trace recognition of calcium channel blocker drug amlodipine besylate (ADB) using cyclic voltammetry and electrochemical impedance spectroscopy measurements. Kinetic parameters like electron transfer coefficient (α), charge due to adsorption (Qads), surface coverage (Γ), charge transfer coefficient (Rct), and apparent electron-transfer rate constant (kapp) for the designed electrodes were evaluated. The nanoparticles based electrochemical sensor displayed high sensitivity, good selectivity and favorable catalytic ability for the oxidation of amlodipine besylate. The fabricated electrodes showed good reproducibility and stability towards the determination of anti-hypertensive drug ADB.",

keywords = "Amlodipine besylate, Electrochemical sensor, Functionalized carbon nanotubes",

author = "Naikoo, {Gowhar A.} and Pandit, {Umar J.} and Sheikh, {Mehraj U.D.} and Hassan, {Israr Ul} and Khan, {Gulzar A.} and Bhat, {Ajmal R.} and Ratnesh Das and Ridha Horchani",

note = "Publisher Copyright: {\textcopyright} 2020, Springer Nature Switzerland AG.",

year = "2020",

month = may,

doi = "10.1007/s42452-020-2807-z",

language = "English",

volume = "2",

journal = "SN Applied Sciences",

issn = "2523-3971",

publisher = "Springer Nature",

number = "5",

}

TY - JOUR

T1 - Synergistic effect of carbon nanotubes, copper and silver nanoparticles as an efficient electrochemical sensor for the trace recognition of amlodipine besylate drug

AU - Naikoo, Gowhar A.

AU - Pandit, Umar J.

AU - Sheikh, Mehraj U.D.

AU - Hassan, Israr Ul

AU - Khan, Gulzar A.

AU - Bhat, Ajmal R.

AU - Das, Ratnesh

AU - Horchani, Ridha

PY - 2020/5

Y1 - 2020/5

N2 - The electrochemically functionalized multiwalled carbon nanotubes/copper nanoparticles (fMWCNT/CuNPs) carbon paste electrode (fMWCNT/CuNPs-CPE) was successfully modified by silver nanoparticles (AgNPs) via electrocatalytic process. The formation of modified electrode (AgNPs/fMWCNT/Cu NP-CPE) was observed by Field Emission Scanning Electron Microscopy and X-ray diffraction techniques. The as-prepared electrodes were explored for the trace recognition of calcium channel blocker drug amlodipine besylate (ADB) using cyclic voltammetry and electrochemical impedance spectroscopy measurements. Kinetic parameters like electron transfer coefficient (α), charge due to adsorption (Qads), surface coverage (Γ), charge transfer coefficient (Rct), and apparent electron-transfer rate constant (kapp) for the designed electrodes were evaluated. The nanoparticles based electrochemical sensor displayed high sensitivity, good selectivity and favorable catalytic ability for the oxidation of amlodipine besylate. The fabricated electrodes showed good reproducibility and stability towards the determination of anti-hypertensive drug ADB.

AB - The electrochemically functionalized multiwalled carbon nanotubes/copper nanoparticles (fMWCNT/CuNPs) carbon paste electrode (fMWCNT/CuNPs-CPE) was successfully modified by silver nanoparticles (AgNPs) via electrocatalytic process. The formation of modified electrode (AgNPs/fMWCNT/Cu NP-CPE) was observed by Field Emission Scanning Electron Microscopy and X-ray diffraction techniques. The as-prepared electrodes were explored for the trace recognition of calcium channel blocker drug amlodipine besylate (ADB) using cyclic voltammetry and electrochemical impedance spectroscopy measurements. Kinetic parameters like electron transfer coefficient (α), charge due to adsorption (Qads), surface coverage (Γ), charge transfer coefficient (Rct), and apparent electron-transfer rate constant (kapp) for the designed electrodes were evaluated. The nanoparticles based electrochemical sensor displayed high sensitivity, good selectivity and favorable catalytic ability for the oxidation of amlodipine besylate. The fabricated electrodes showed good reproducibility and stability towards the determination of anti-hypertensive drug ADB.

KW - Amlodipine besylate

KW - Electrochemical sensor

KW - Functionalized carbon nanotubes

UR - http://www.scopus.com/inward/record.url?scp=85100653882&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85100653882&partnerID=8YFLogxK

U2 - 10.1007/s42452-020-2807-z

DO - 10.1007/s42452-020-2807-z

M3 - Article

AN - SCOPUS:85100653882

SN - 2523-3971

VL - 2

JO - SN Applied Sciences

JF - SN Applied Sciences

IS - 5

M1 - 983

ER -

Synergistic effect of carbon nanotubes, copper and silver nanoparticles as an efficient electrochemical sensor for the trace recognition of amlodipine besylate drug

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this