Psychological burden among women with polycystic ovarian syndrome in Oman: A case-control study

Maha A.H. Sulaiman, Yahya M. Al-Farsi*, Maha M. Al-Khaduri, Mostafa I. Waly, Jumana Saleh, Samir Al-Adawi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)


Purpose: Previous studies in Euro-American populations have shown that women with polycystic ovarian syndrome (PCOS) have increased levels of “psychological burden”. While PCOS has been reported in Arab countries such as Oman, there is a dearth of studies of the occurrence of psychological burden among PCOS women in the Arab region. This study aimed to compare sociodemographic and clinical characteristics of PCOS women diagnosed with non-PCOS women and prevalence of severity of depression, anxiety and stress and to explore the association between PCOS and indices of psychological disturbances after adjusting for potential confounding factors. Patients and methods: This hospital-based case-control study was conducted among women aged 16-49 years. The study included 52 women diagnosed with PCOS (as per Rotterdam 2003 criteria) and 60 control who were PCOS-free. The presence of psychological burden - depression, anxiety and stress - was quantified using Depression, Anxiety and Stress Scale-21 (DASS-21). Results: The crude odds ratios (ORs) generated by logistic regression models indicated an increased risk of depression, anxiety and stress among women with PCOS compared to controls. The adjusted OR also indicated an increased risk of depression (OR =1.10; 95% confidence interval [CI] 0.50, 2.43), anxiety (OR =1.09; 95% CI 0.47, 2.52) and stress (OR =1.45; 95% CI 0.68, 3.12), However, no statistical differences were observed along the three psychological distresses (p>0.05) between the two study groups. Conclusion: The study indicates that the presence of PCOS is associated with an increased risk of psychological burden. If this study will withstand further scrutiny, meeting psychological needs of such population would need to be contemplated.

Original languageEnglish
Pages (from-to)897-904
Number of pages8
JournalInternational Journal of Women's Health
Publication statusPublished - Dec 12 2017


  • Anxiety
  • Case-control
  • Depression
  • Oman
  • PCOS
  • Stress

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynaecology
  • Maternity and Midwifery


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