Introduction to Systematic Reviews and Meta-analyses of Therapeutic Studies

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A systematic review is a specific and reproducible method to search, identify, select, appraise, and summarize all studies relevant to a particular health care question. In this paper, we will review the concept of level of evidence, define the terms systematic review and meta-analysis, and outline the steps in performing a systematic review and meta-analysis with an illustrative example. We will also introduce some important concepts in systematic reviews and meta-analyses like heterogeneity, publication bias, forest plots, and quality assessment. Finally, this review will focus on systematic reviews addressing therapeutic research questions.

Original languageEnglish
Article numbere428
JournalOman Medical Journal
Issue number5
Publication statusPublished - Sept 30 2021


  • Clinical Trial
  • Meta-Analysis
  • Systematic Review

ASJC Scopus subject areas

  • General Medicine

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