Herbal supplements and hepatotoxicity: A short review

Haszianaliza Haslan, Farihah Haji Suhaimi, Srijit Das

Research output: Contribution to journalReview articlepeer-review

12 Citations (Scopus)


Herbal products have gained popularity over the past few decades. The reasons attributed to the rise in popularity are cheaper costs, easy availability, patient compliance and fewer side effects. However, liver toxicity following consumption of herbal remedies is on the increase. Thus, there is an urgent need to understand the mechanism of action of the herbal supplements on the liver. Occasionally, herbal supplements may also interact with conventional drugs. The present review focusses on a few herbs such as Aloe barbadensis, Atractylis gummifera, Centella asiatica, Mitragyna speciosa, Morinda citrifolia, Larea tridentata, Symphytum officinale, Teucrium chamaedrys and Xanthium strumarium, which are reported to cause hepatotoxicity in humans and animals. Prior knowledge on hepatotoxicity caused by herbs may be beneficial for clinicians and medical practitioners.

Original languageEnglish
Pages (from-to)1779-1784
Number of pages6
JournalNatural Product Communications
Issue number10
Publication statusPublished - Oct 2015


  • Alternative medicine
  • Complementary medicine
  • Herbs
  • Liver
  • Toxicity

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery
  • Plant Science
  • Complementary and alternative medicine


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