Borna disease in a dog with lethal meningoencephalitis

H. Weissenbock*, N. Nowotny, P. Caplazi, J. Kolodziejek, F. Ehrensperger

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

70 Citations (Scopus)


A dog was euthanatized because of progressive neurological signs. Histologically, a nonsuppurative meningoencephalitis was found. By immunohistochemistry, in situ hybridization, and nested PCR procedures, Borna disease virus (BDV) antigen and BDV-specific RNA were demonstrated in brain tissues of the dog. The nucleotide sequence of the PCR product showed 94 to 98% homology to published BDV sequences. This is the first description of Borna disease in a dog.

Original languageEnglish
Pages (from-to)2127-2130
Number of pages4
JournalJournal of Clinical Microbiology
Issue number7
Publication statusPublished - 1998

ASJC Scopus subject areas

  • Microbiology (medical)


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